first_imgWATCH: “Everyone is fighting so hard to get on” – Pat Ryan on competitive camogie squads Limerick’s National Camogie League double header to be streamed live Twitter Previous articleSt John’s Cathedral to play host to Southwest Michigan ChoraleNext articleCNN reporter addresses CIPD Mid West forum Alan Jacques WhatsApp Limerick Ladies National Football League opener to be streamed live Facebook WELL done to Sean O’Shea from Athea in County Limerick who is the lucky winner of one pair of tickets and two large combo meals for a film of his choice at the Odeon Cinema in Castletroy.The answer to our film competition in last week’s Limerick Post was Patty Jenkins.Sign up for the weekly Limerick Post newsletter Sign Up More tickets to give away to the Odeon Cinema in this Thursday’s edition. Predictions on the future of learning discussed at Limerick Lifelong Learning Festival NewsLocal NewsCompetition winnerBy Alan Jacques – June 12, 2017 874 center_img Print TAGScinemacompetitionlimerickOdeon CinemaOdeon LimerickWonder Woman Advertisement RELATED ARTICLESMORE FROM AUTHOR Email Linkedin Limerick Artist ‘Willzee’ releases new Music Video – “A Dream of Peace” Billy Lee names strong Limerick side to take on Wicklow in crucial Division 3 clashlast_img read more

first_imgOct 5, 2005 (CIDRAP News) – Scientists today reported findings that may help explain what made the 1918 pandemic influenza virus so deadly and that reveal similarities between that virus and the H5N1 avian influenza virus now circulating in Asia.Scientists at the Centers for Disease Control and Prevention (CDC) reconstructed the virus and tested it in laboratory animals, which quickly died. The CDC says the work, to be reported in Science, will enhance preparedness for the next flu pandemic, a potential benefit believed to justify the risk of recreating the virus and publishing the information.In the other study, researchers at the Armed Forces Institute of Pathology (AFIP) report that the close resemblance of the 1918 virus to avian flu viruses suggests that the 1918 virus was an avian strain that managed to adapt to humans without first acquiring any genes from existing human flu viruses. Further, the researchers found that several of the same mutations that differentiated the 1918 virus from avian flu viruses are found in the H5N1 virus, which has killed more than 60 people in Asia. The report appears in Nature.The 1918 flu pandemic, regarded as the worst in history, killed as many as 100 million people. In recent years scientists have been able to learn the structure of the H1N1 virus that caused it by analyzing samples preserved from pandemic victims, including tissue from a frozen body exhumed in Alaska and material stored in the AFIP’s warehouse of autopsy samples.In a joint statement today, the directors of the CDC and the National Institute of Allergy and Infectious Disease (NIAID), Dr. Julie Gerberding and Dr. Anthony Fauci, said, “For the first time, researchers have deciphered the entire gene sequence of the 1918 virus and have used sophisticated techniques to assemble viruses that bear some or all of these genes so their effects can be understood.”Importantly, they have identified gene sequences that may predict when an influenza virus strain is likely to spread among humans. They also have determined in the test tube and in mice which genes are most likely to account for the lethal effects of the 1918 virus.” The statement was released by the NIAID.”The new studies could have an immediate impact by helping scientists focus on detecting changes in the evolving H5N1 virus that might make widespread transmission among humans more likely,” the statement said.Because of concern that terrorists could exploit the information, both articles were reviewed by the National Science Advisory Board for Biosecurity before publication, according to the NIAID statement. The board unanimously endorsed publishing them.”The rationale for publishing the results and making them widely available to the scientific community is to encourage additional research at a time when we desperately need to engage the scientific community and accelerate our ability to prevent pandemic influenza,” Gerberding and Fauci stated.Resurrection of the 1918 virusIn the Science article, Terrence M. Tumpey and colleagues report that they generated a flu virus bearing all eight gene segments of the 1918 virus in order to study what made it so virulent. They exposed groups of mice to that virus and to other viruses in which some of the 1918 virus’s genes were replaced by genes from recent flu viruses.The 1918 virus turned out to be extremely virulent. Mice infected with it died in as little as 3 days, and mice that survived as long as 4 days had 39,000 times as many virus particles in their lungs as did mice infected with a control flu virus, a Texas strain of H1N1 from 1991. All the mice infected with the 1918 virus died, while those exposed to the Texas strain survived. Further, the 1918 virus was at least 100 times as lethal as an engineered virus that contained five 1918 genes and three genes from the Texas H1N1 strain.The researchers found that the mice had severe inflammation in their lungs and bronchial passages—findings very similar to those in people who died of the 1918 virus. However, the virus did not spread in the mice to the brain, heart, liver, or spleen.The scientists also tested the virus’s behavior in a laboratory culture of human lung cells. Within 24 hours, the lung cells released at least 50 times as much virus as did lung cells infected with the Texas H1N1 strain.In comparing the 1918 virus with recombinant viruses containing only some of the 1918 genes, the researchers found that the 1918 hemagglutinin and polymerase genes were “essential for optimal virulence.” The complete 1918 virus was more pathogenic for mice than any other human flu virus that has been tested, the report says.Likeness between 1918 virus and avian strainsThe Nature article, by Jeffery Taubenberger and colleagues from the AFIP, reports on an analysis of the three polymerase genes in the 1918 virus, the last three genes to be fully spelled out. The researchers found that these genes closely resembled their counterparts in avian flu viruses.”The polymerase protein sequences from the 1918 human influenza virus differ from avian consensus sequences at only a small number of amino acids, consistent with the hypothesis that they were derived from an avian source shortly before the pandemic,” the report states.Accordingly, the researchers propose that the 1918 virus was not a “reassortant,” like those that caused the smaller pandemics of 1957 and 1968. In those cases, avian flu viruses traded some genes with human-adapted flu viruses to spawn new hybrids. The 1918 virus was “an entirely avian-like virus” that somehow adapted to humans, they suggest.The report says only 10 amino-acid changes in the polymerase genes consistently distinguish the 1918 virus and subsequent human flu viruses from the same genes in avian viruses. It adds, “A number of the same changes have been found in recently circulating, highly pathogenic H5N1 viruses that have caused illness and death in humans and are feared to be the precursors of a new influenza pandemic.”A news story accompanying the report in Nature says that all eight genes from the 1918 virus differ in important ways from other human flu genes, which suggests that none of the genes came from a flu strain that had previously infected people. “It is the most bird-like of all mammalian flu viruses,” Taubenberger is quoted as saying.According to the Nature news story, some scientists are questioning the wisdom of recreating the 1918 virus and publishing information on how it was done. Richard Ebright, a bacteriologist at Rutgers University in New Jersey, said Tumpey and colleagues “have constructed, and provided procedures for others to construct, a virus that represents perhaps the most effective bioweapons agent now known.”In a news release, the CDC said it used “stringent” precautions in the research. “The work was done in a high-containment Biosafety Level 3 lab with enhancements that include special provisions to protect both laboratory workers and the public from exposure to the virus,” the agency said.Taubenberger JK, Reid AH, Lourens RM, et al. Characterization of the 1918 influenza virus polymerase genes. (Letter) Nature 2005 Oct 6;437(7060):889-892 [Full text]Tumpey TM, Basler CF, Aguilar PV, et al. Characterization of the reconstructed 1918 Spanish influenza pandemic virus. Science 2005 Oct 7;310(5745):77-80 [Abstract]See also:Oct 5 CDC Press release 5 NIAID Press release read more

first_imgThe following counties had the most accommodation units from the group Hotels and similar accommodation for persons with reduced mobility and disabilities: Split-Dalmatia (20,5%), Istria (14,0%), Primorje-Gorski Kotar (13,1%), Zadar 10,2%), Dubrovnik-Neretva (9,7%) and the City of Zagreb (9,4%), which is a total of 76,9%. According to the Central Bureau of Statistics (CBS) in the Republic of Croatia, out of a total of 1 accommodation facilities from the group Hotels and similar accommodation, in which tourist nights were realized in 074, 2018 accommodation facilities (355%) had accommodation units (rooms and apartments) for people with reduced mobility and disabilities. In the Split-Dalmatia County, most accommodation units are for people with reduced mobility and disabilities In 2018, a total of 1 accommodation units (515 rooms and 1 suites) were available in the group Hotels and similar accommodation for persons with reduced mobility and disabilities. A total of 33,1% of hotel accommodation facilities in Croatia have accommodation facilities for people with reduced mobility and disabilities. center_img In other counties, 23,1% of accommodation units for persons with reduced mobility and disabilities were available. Hotels have the most rooms and suites for people with reduced mobility and disabilities In the structure of accommodation facilities from the group Hotels and similar accommodation that had accommodation units (rooms and apartments) for persons with reduced mobility and with disabilities, most accommodation units were in hotels (83,9%). Other facilities from the group Hotels and similar accommodation had 16,1% of accommodation units at their disposal.last_img read more

first_imgBNP Paribas and Kempen Capital Management are currently available as asset managers, but no insurer has yet been “linked up”, they said.The PPI has contracted APG and its subsidiary InAdmin for pensions provision and communication.According to Ronald Ketellapper, trustee at i-PensionsSolutions, Credit Suisse and Swiss Re have merely financed the PPI, and that their business model would focus on selling services to affiliated asset managers and insurers. PPIs are an alternative pensions vehicle for low cost and transparent DC plans in the second pillar for employers. Swiss bank Credit Suisse and re-insurer Swiss Re have launched a PPI pensions vehicle for defined contribution arrangements in the Netherlands.The companies said their PPI – dubbed i-PensionSolutions – would be the first with a “truly open architecture”, allowing a participating employer to opt for an asset manager of its own choice.The employer will also be able to select an insurer if it chooses to insure additional risk, such as with a partner’s pension or in the event of labour disability. However, before the employer can make a selection, the preferred asset manager or insurer must be affiliated with the “platform” of i-PensionSolutions, according to Credit Suisse and Swiss Re.last_img read more

first_imgThe towns of Zarraga and Carles, onthe other hand, each hosts a regional evacuation center built by the Office ofCivil Defense and National Disaster Risk Reduction and Management Council. “Akonag-design dasun ginpa-interpret ko saProvincial Engineer’s Office paramagasunod gid sa international standards,” said Bionat. This is the evacuation center of the Municipality of Oton, Iloilo. Here, displaced residents can seek shelter in times of disaster such as flooding, landslide, earthquake or fire, among others. The Iloilo provincial government will build two evacuation centers next year in the municipalities of Mina in the 3rd District and Tigbauan in the 1st District. Each center will cost P23.1 million. IAN PAUL CORDERO/PN ILOILO – The provincial governmentwill build two evacuation centers next year in the municipalities of Mina inthe 3rd District and Tigbauan in the 1st District. Each evacuation center will have astockroom, comfort rooms, bleachers, ventilation, water system, and conferenceroom. Towns that already have evacuationcenters are Estancia, Balasan, Banate, Oton, Dueñas, Ajuy, and Pototan. Bionat said the local government unitsof these towns offered to donate lots where to construct the evacuation centers– within schools or near schools. Why in Mina and Tubungan? “The goal,” according to Bionat, “is foreach local government unit to have an evacuation center to do away with thecurrent practice of turning schools into temporary evacuation centers whendisaster strikes such as flooding, landslide, earthquake or fire.” Each center will cost P23.1 million,according to Provincial Disaster Risk Reduction and Management Office (PDRRMO)chief Dr. Jerry Bionat. Each regional evacuation center costP35 million to build./PNlast_img read more

first_imgIn the eighth finals of the Challenger in St. Remy in France, BH tennis player Mirza Basic played against German Yannick Hanfmann, and defeated him with the score 2: 0 in sets (6: 3, 6: 3).After eliminating the 152nd player in the world, Belgian Kimmer Coppejans, in the 1st round with the score 2: 0 in sets (7: 5, 6: 1), (, his opponent in the second round was 325th tennis players, Yannick Hanfmann from Germany.Our tennis player resolved the first set in his favor with the score 6: 3 in games after 32 minutes of play.In the second set, Mirza also dominated and won with the score 6: 3 in games. With the victory in this match, Basic advanced to the quarterfinals of the Challenger in St. Remy, and his opponent will be Marco Trungelliti from Argentine (120th on the ATP list).Challenger in St. Remy, 2nd Round:Mirza Basic – Yannick Hanfmann 2:0 (6:3, 6:3)(Source: D. B./ read more